The first textbook in the program, Principles of Biology, is a research-oriented, affordable interactive textbook Featured eBooks. Essentials of Genetics. Basic . This unit answers each of these questions, and it also provides a basic overview of how DNA Cell division, the basic means by which genetic information is passed from generation to . Source Material for the Essentials of Genetics eBook. Department of Genetics, University of Alabama at Birmingham,. 3rd Avenue The basic unit of genetic function is the gene, the chemical basis for which.
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I had never taken genetics as an undergrad so I read this book in preparation for genetics in med school. It is an easy read - very basic and clear, but definitely. Learning Basic Genetics with Interactive Computer Programs PDF; ebooks can be used on all reading devices; Immediate eBook download after download. Page 1 of 1. Introduction to Essentials of Genetics | Learn Science at Scitable. 8/9 / bartlocawinlo.ml
A Brief History of Genetics: This eBook will take students through some of the seminal experiments in genetics, allowing This eBook will take students through some of the seminal experiments in genetics, allowing students to review some of the data and literature that has provided us with our foundational understanding of our genetic material.
The Elaboration of the This is the Central Dogma, a term coined by Francis Crick in Since the Since the discovery of the helical structure of DNA, scientists began to elucidate the value of that structure.
The double helix provided both a template and storage mechanism. Mechanisms of transcription and translation take the information encoded in the DNA helix and make it "work" in cells, through the production of proteins defined by nucleic acid coding regions.
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Today, we know that the Central Dogma is much more complex. Anyone interested in exploring protein-coding genes using the University of California Santa Cruz Meant for all audiences, this eBook is a tutorial for those who have little or no experience or those advanced users who are not yet familiar with many of the gene-oriented browser features.
The Important X Chromosome. This series of articles reviews some important concepts about the X chromosome, such as sex This series of articles reviews some important concepts about the X chromosome, such as sex determination, X-linkage and X-inactivation.
Chromatin in Eukaryotic In eukaryotes, the tight or loose packaging of the genes in chromatin DNA plus specific proteins In eukaryotes, the tight or loose packaging of the genes in chromatin DNA plus specific proteins can control whether the genes can be expressed to form their encoded product. Chromatin is usually not "permissive" but it can be modified in specific areas to open it up for transcription of the genes.
Chromatin is opened by remodeling complexes. Nucleosomes, eight histone molecules plus associate DNA of about nucleotides in length, can be "closed" by removing acetyl groups on the tails of the histones, or "opened" by placing acetyl groups there.
Placement of acetyl or methyl groups on a specific histone can have opposing effects or additive effects on gene expression.
The gene expression effect of histone modification placements is called the histone code. DNA itself can be methylation and that also regulates gene expression, generally to turn off the gene.
Types of Genetic Disease. Genes play a role in many human disorders. Some rare disorders are linked to mutations in single Some rare disorders are linked to mutations in single genes that follow Mendelian inheritance patterns.
Other disorders are regulated by multiple genes, or multiple genes together with the environment.
Ricki Lewis: Human Genetics: The Basics
Still others are the result of chromosomal abnormalities. Chromosomes and Disease.
This eBook will help you understand the ways that chromosomes are linked to some human diseases and This eBook will help you understand the ways that chromosomes are linked to some human diseases and will discuss some of the techniques involved in studying chromosomes. Genomes and Disease.
However, the sequence alone actually tells us little about our biology. Now, scientists are examining this massively long sequence for clues about how variation in our genetic sequence contributes to disease.
Genes and the Environment: This eBook takes students through our basic understanding of inheritance.
Then we examine the Then we examine the complexity of polygenic traits and phenotypes affected by environmental conditions. Finally we explore how scientists study the genetic component of certain phenotypes. Genetic Variation and An Overview of Human Genetic Variation. Human Population Genetics.
Comparative Genomics and Genome Evolution. Human Evolution. Part 4: Human Genetic Disease Chromosomal Abnormalities and Structural Variants.
Molecular Pathology: Connecting Phenotypes to Genotypes. Mapping and Identifying Genes for Monogenic Disorders. Cancer Genetics and Genomics.
In , this number had more than doubled, reaching , By the end of , a total of 1. One of the motivations behind OER is to reduce cost and expand access. Many students and faculty seek affordable alternatives. The global effort to create OER textbooks is recognized and has already delivered some success, but the need for more high-quality OER textbooks is urgent and still largely unmet. As of January , 29 professional-grade OER higher education textbooks have been released by OpenStax College, which aims to offer textbooks for the most heavily attended college courses in the US.
The current production model resembles the traditional textbook production process—slow, with little turnover—and may not be suitable for education in rapidly evolving scientific fields. Thus, directed participation might be required, possibly through social learning models that derive from the perception that understanding emerges from interactions about content [ 8 ]. Many learners benefit from an interactive experience, but most OER textbooks lack support for emerging approaches to social learning.
It is our expectation that, when implemented appropriately, the creation of OER e-textbooks should be able to both lower cost and improve learning. To contribute to the OER movement and to demonstrate the use of an open-access platform towards the creation of OER, we first developed an online textbook creation platform, CuboCube, and then student authors tested and assessed the system by creating an e-textbook.
The mathematical term cubocube refers to a number taken to the third power two times [ ], which we believe reflects a universe of complex educational spaces that is enabled within the CuboCube system. A world of worlds. While in this report we focus attention on aspects of CuboCube to enable readers to understand the experiences of students in this project, it is not our intention to promote CuboCube over alternatives.
CuboCube aims to facilitate textbook development and promote social learning. CuboCube serves two purposes: students can learn and create content for an advanced cancer topic of their interest, and the created content can be reused and updated by future students enrolled in similar courses. The system was beta-tested by 35 students in , and the content was subsequently revised and expanded by a student cohort in and a student cohort in The mechanism by which DNA is passed from one generation of cells to the next is a combination of DNA replication and cell division.
His most recent research has focused on developmental disorders and developmental control genes. Many students and faculty seek affordable alternatives. World Library of Science Chat. Although it was developed with non-native speakers of English in mind, it should prove useful for native speakers, too.
Principles of Heredity. Competing interests: The authors have declared that no competing interests exist. Many learners benefit from an interactive experience, but most OER textbooks lack support for emerging approaches to social learning.
Packaging DNA into Chromosomes: Created by seasoned communicators, English Communication for Scientists provides no-nonsense, directly applicable guidelines, illustrated with examples of written documents, oral presentations, and more.
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